Anabolic Steroids - Topic OverviewAnabolic steroideq profile test called anabolic-androgenic steroiddrug that mimics the male hormone testosterone in its ability to increase anabolic effects directly relate to growth of muscle tissue and in its promotion of male secondary sex characteristics. Anabolic steroids are used medically in humans to treat a variety of conditions, including anemiabreast cancerhypogonadismshort stature, malnutritionosteoporosisand human immunodeficiency virus HIV wasting syndrome. The drugs are also anabolic effects directly relate to in veterinary medicine e. Some examples of anabolic steroids are nandrolone, oxandrolone, oxymetholone, stanozolol, and trenbolone acetate. Anabolic steroids target the androgen receptorthe natural biological receptor for testosterone and its metabolite dihydrotestosterone. Stimulation of the androgen receptor results in anabklic growth, leading to an increase in muscle size.
Effects of androgenic-anabolic steroids in athletes. - PubMed - NCBI
Anabolic steroid , also called anabolic-androgenic steroid , drug that mimics the male hormone testosterone in its ability to increase the growth of muscle tissue and in its promotion of male secondary sex characteristics. Anabolic steroids are used medically in humans to treat a variety of conditions, including anemia , breast cancer , hypogonadism , short stature, malnutrition , osteoporosis , and human immunodeficiency virus HIV wasting syndrome.
The drugs are also used in veterinary medicine e. Some examples of anabolic steroids are nandrolone, oxandrolone, oxymetholone, stanozolol, and trenbolone acetate. Anabolic steroids target the androgen receptor , the natural biological receptor for testosterone and its metabolite dihydrotestosterone. Stimulation of the androgen receptor results in cell growth, leading to an increase in muscle size. It also leads to virilization—the development of masculine traits, including increased libido and deepening of the voice.
Anabolic steroids are commonly abused by human athletes to build muscle and improve strength. The drugs are also used in livestock to augment muscle mass, and they are sometimes given to racehorses to increase stamina and heighten performance.
The use of anabolic steroids is either forbidden or closely controlled in most human and some equine sports. Abuse of anabolic steroids, however, can result in significant harm to the body. In humans, abuse can lead to coronary heart disease , sexual and reproductive disorders, immunodeficiencies , liver damage, stunted growth, aggressive behaviour , susceptibility to connective tissue injury, and in females irreversible masculinization.
Similar side effects can occur in livestock and other animals. In horses , for example, anabolic steroids can cause liver damage and weakening of the tendons and can result in decreased testis size and sperm production in stallions and altered reproductive cycling in mares.
Anabolic steroids are readily detected in urine and blood. We welcome suggested improvements to any of our articles. You can make it easier for us to review and, hopefully, publish your contribution by keeping a few points in mind.
Your contribution may be further edited by our staff, and its publication is subject to our final approval. Unfortunately, our editorial approach may not be able to accommodate all contributions. Our editors will review what you've submitted, and if it meets our criteria, we'll add it to the article. Please note that our editors may make some formatting changes or correct spelling or grammatical errors, and may also contact you if any clarifications are needed.
The Editors of Encyclopaedia Britannica. Learn More in these related Britannica articles: There was also concern that the amateur spirit of the Games had been undermined by the growing commercial influence on sports in the West and the pervasive government control of athletes in the Eastern bloc countries. Tests for anabolic steroids and other substances improved, but so did doping practices, with the design of new substances often a year or two ahead of the new tests.
When metre-sprint champion Ben Johnson of Canada tested positive for the drug stanozolol at the Summer Games…. The anabolic steroids are testosterone derivatives that provide anabolic activity with less stimulation of growth of the sexual organs.
Anabolic steroid s have been used to increase muscle strength and endurance. However, this practice can have serious long-term consequences, such as the development of atherosclerotic disease because….
More About Anabolic steroid 9 references found in Britannica articles Assorted References development of physical culture In physical culture: Weightlifting effect upon human aging In human aging: Endocrine system uses In steroid: Androgens and anabolic steroids In sports: Human performance and the use of drugs characteristics of androgens In therapeutics: Hormones steroid hormones In steroid hormone history of baseball In baseball: Montreal, Canada, In Olympic Games: Doping and drug testing.
Help us improve this article! Contact our editors with your feedback. You have successfully emailed this. You may find it helpful to search within the site to see how similar or related subjects are covered. Any text you add should be original, not copied from other sources. At the bottom of the article, feel free to list any sources that support your changes, so that we can fully understand their context. Internet URLs are the best. Thank You for Your Contribution! There was a problem with your submission.
Please try again later. Keep Exploring Britannica Quantum mechanics. Quantum mechanics, science dealing with the behaviour of matter and light on the atomic and subatomic…. Light, electromagnetic radiation that can be detected by the human eye.
If you prefer to suggest your own revision of the article, you can go to edit mode requires login. Thank you for your feedback.