Masteron (Drostanolone)Masteron is one of those steroids that has a bit of mystique behind it as it is both commonly overrated as well as underrated depending on the circle in-which mssteron travel. One of the more masteron anabolic steroids counterfeited steroids around; when masteron anabolic steroids do possess legit Masteron the most common form will anadrol dianabol attached anapolon pre workout the Propionate ester with an Enanthate ester version also being available. Further, like many anabolic steroids there is a strong medical purpose outside of performance enhancement but masteron anabolic steroids, the purpose of Masteron-Propionate in the medical field is a good bit different than most other anabolic steroids. Developed to treat breast cancer Masteron-Propionate is one of the more masteron anabolic steroids medications for this purpose, especially when coupled with Tamoxifen-Citrate Nolvadex and masteron anabolic steroids alone masteron anabolic steroids the steroid a ahabolic of a unique nature. Most anabolic steroids that were developed with medical intent are generally done so in an effort to fight muscle wasting diseases but as you can see this is not the case with Masteron. Masteron-Propionate appears to have the ability to reduce estrogen in the body to a degree and as estrogen is the enemy of a breast cancer patient it is very easy to see how this would benefit the individual.
Masteron - Steroids Profile - ghid-supraveghere.info
Masteron is the trade name for the anabolic steroid Drostanolone. Materon is an injectable oil-based anabolic steroid, and is derived from Dihydrotestosterone DHT , which makes Masteron a member of the DHT-derived family of anabolic steroid derivatives and analogues.
Essentially, all anabolic steroid analogues and derivatives are all modifications in one way or another of the three primary anabolic steroids naturally found in all humans: Testosterone, Dihydrotestosterone, and Nandrolone. Other anabolic steroids that belong in this family of DHT-derivatives include: Anavar , Winstrol, Anadrol , Primobolan , and various others. Masteron is not regarded as a very strong anabolic steroid but neither is it a weak one. Its anabolic strength is generally regarded as moderate at best anabolic rating of 62 — , while its androgenic strength is fairly low 25 — This demonstrates a stark difference when compared to Testosterone , which is the number one natural and original anabolic steroid, and is used as the reference measuring bar by which all other anabolic steroids are compared to and measured against.
Testosterone in comparison holds an anabolic and androgenic strength rating of for both respectively. The origins of this compound are quite interesting, as Syntex had synthesized and developed this anabolic steroid. Syntex was also known for the development of other popular anabolic steroids as well, such as Anadrol and Methyldrostanolone AKA Superdrol. It would not be until about 10 years later after the publishing of its details that Masteron would finally be released onto the market.
It was Lilly that ended up marketing Masteron under the brand name known as Drolban on the American market. Syntex also marketed this anabolic steroid, only they would look after its marketing and distribution on the international market instead. Masteron was approved by the FDA at first as an antineoplastic agent in the treatment of female breast cancer patients.
Masteron in particular fit very well into this role, as its lower and weaker androgenic strength rating in comparison to Testosterone could prove to be very beneficial in female users, as the incidence of virilization symptoms would be less prominent with Masteron than many other anabolic steroids which are known to possess strong androgenic strength ratings. Even the prescription information and guidelines expounded this fact, stating that there is far less of a probability of developing virilization with Masteron in comparison to equal Testosterone Propionate doses.
However, the problem here was that the initial prescription guidelines for females was that of mg weekly of Masteron, which evidently proved to be too high of a dose for females as evidenced by the fact that virilization did occur in many patients at that dose.
Virilization had also become an issue in female patients that had been administered Masteron in the long term. As more effective breast cancer treatments were discovered and developed, Masteron began to lose its value in the medical field, and many different pharmaceutical manufacturers began to slowly discontinue sale and production of this compound during this time. Drolban itself was officially pulled from the American market in the late s, and two other branded Masteron preparations were soon after pulled from the market as well.
Masteron today still remains on the list of approved medications, but it is not currently being manufactured, and therefore not being sold on American or any Western markets. The specific name for Masteron is actually Dromostanolone Drostanolone was a slightly more abbreviated name given to the compound shortly after its release. As mentioned previously, it is a modified derivative of DHT Dihydrotestosterone , placing it into the family of DHT-derivatives and analogues.
Masteron is a modified form of DHT, where a methyl group at the 2 nd carbon known as carbon alpha atom. This modification is what is known to be responsible for the slight anabolic strength increase in comparison to Testosterone. This methyl group addition increases the anabolic strength by way of granting Masteron an increased resistance to being metabolized into inactive metabolites by the enzyme 3-hydroxysteroid dehydrogenase.
This enzyme is present in large quantities in muscle tissue, and is the enzyme that serves to metabolize any DHT that enters muscle tissue into two inactive metabolites: This is therefore the reason as to why DHT is not anabolic in muscle tissue at all, and many chemists and biologists believe that if the enzyme 3-hydroxysteroid dehydrogenase did not exist in muscle tissue, that DHT would actually be a very potent and powerful anabolic steroid.
There exist two different variants of Masteron: Drostanolone Propionate , and Drostanolone Enanthate. The most popular variant is the Propionate variant, followed in popularity by the Enanthate variant. The explanation here will use Drostanolone Propionate as the example.
Propanoic acid is bonded to the beta hydroxyl group on the Drostanolone Masteron chemical structure. The primary reason for the augmentation of its half-life and release rate is because once Drostanolone Propionate enters the bloodstream, enzymes in the body will break the bond between the ester and the hormone, which takes varying amounts of time the time taken for the bonds to be broken is dependent on the size of the ester — the longer and larger it is, the longer it will take.
The end result is that the ester is removed from the hormone by enzymes, and what is left is pure Masteron or any anabolic steroid that was previously esterified that is now free to do its work in the body.
This process of enzymes cleaving off the ester from the Testosterone molecule is what is responsible for the slower release rates and extended half-lives. As a result, Drostanolone Propionate possesses a half-life of 2. Because Masteron is a DHT-derivative, it retains some of the same characteristics as its parent hormone, one of which is its inability to interact with the aromatase enzyme. The aromatase enzyme is the enzyme responsible for the conversion of androgens into Estrogen, of which Masteron is invulnerable to this process.
Therefore, Masteron will exhibit no Estrogenic side effects at any dose, making Masteron completely void of the following risks: Individuals using Masteron will only experience lean mass gains without the addition of water weight, which would otherwise serve to create a very puffy, soft, and bloated looking physique. This leads to the next major property of Masteron.
Masteron has been demonstrated as being a moderate aromatase inhibitor, as well as possibly acting to block Estrogen at receptor sites on breast tissue  . Masteron works to inhibit the aromatase enzyme, thereby eliminating the ability for estrogen to be formed from aromatizable anabolic steroids through the process of aromatization.
Essentially, this effectively reduces any water retention as Estrogen levels continue to decline from increasing numbers of disabled aromatase enzymes. This is due in large part to the fact that Masteron is a DHT-derivative.
Having been derived from DHT, it therefore possesses all of the same or similar attributes and features that DHT does. This includes the inability to interact with the aromatase enzyme, and therefore be completely void of any Estrogen-related side effects. As previously mentioned, Masteron is totally void of any estrogenic side effects by virtue of the fact that it is a DHT-derivative.
Not only does it completely avoid aromatization conversion into Estrogen , evidence suggests that it behaves as a mild aromatase inhibitor as well. Side effects resultant of Estrogen buildup such as water retention, bloating, fat retention and gain, and the development of gynecomastia are completely avoided or reduced with the use of Masteron.
Though Masteron holds a weaker androgenic strength rating than Testosterone itself, androgenic side effects are still indeed possible with this compound, especially among those who may be particularly sensitive. Masteron side effects that include androgenic side effects include: Virilization the development of male characteristics in women is also a risk with female use, though its use in female breast cancer patients should attest to its acceptable nature as a female-use compound.
Masteron side effects in particular include greater negative impacts on cholesterol and the cardiovascular system than some other compounds. Masteron cycles tend to be quite limited in their dynamic and application. This is because of the nature of the compound being unfavorable for bulking, strength gain, and the like.
Unfortunately, as a cutting or fat loss agent, there are much better anabolic steroids in existence at the disposal of the individual than Masteron. Even in cutting or fat loss cycles, Masteron is usually not a key-role compound involved. The cycle length of Masteron cycles are usually in the range of 8 — 10 weeks, mostly due to its short-ester nature.
Some bodybuilders will elect to utilize Masteron only within the final 2 — 4 weeks of a cycle leading up into a show or a photoshoot, only to gain advantage of its physique enhancement abilities.
This generally looks like a cycle performed for 10 weeks, with compounds such as Testosterone Propionate, Trenbolone Acetate, and Anavar being used.
Towards the 6 or 8-week mark of said cycle, Masteron would be included into the mix alongside perhaps a removal of one of the other compounds , and run right to the end of the 10 th week. Within the medical arena, Masteron was utilized in the treatment of female breast cancer patients. The duration of this treatment was recommended to be 8 weeks at a minimum. By the 8 — week mark, the physician would provide an assessment of the patient and their progress, and based upon the progress and the prognosis, Masteron may be utilized indefinitely in the treatment of the cancer.
Female athletes and bodybuilders would find 50 — mg per week a safe and acceptable dosage. For athletic and bodybuilding purposes for male users, Masteron dosages are in the range of — mg per week, and the lower end of this range mg is commonly utilized for pre-contest preparation and cycles.
It must be remembered that Masteron is a weak compound where the addition of strength, mass, and muscle is concerned, and there are more effective and cheaper compounds for this purpose. Masteron is not as popular as many other anabolic steroids, and would be considered low-moderate in popularity on the market. Those looking to buy Masteron will find that it is quite the expensive anabolic steroid as well, and is by no means a cheap compound, even as an underground product.
Pharmaceutical grade Masteron is extremely rare and almost nonexistent on the market, leaving nearly all Masteron products available for sale as underground lab UGL products. The only pharmaceutical grade Masteron product that technically still exists is known as Dromostan, manufactured by Xelox Company out of Mayanmar. However, this product is neither Drostanolone Propionate or Enanthate. Instead, it is Drostanolone base, an un-esterified variant of Drostanolone. To most athletes and bodybuilders, this is essentially a useless product.
Although it can still be used if acquired, the lack of an ester would result in the half-life of Drostanolone to be extremely short and therefore require injections possibly at least once per day and as many as multiple times per day.
Once again, these are all strictly underground products, as pharmaceutical grade Masteron is pretty well nonexistent on the anabolic steroid black market. Masteron Drostanolone, Dromostanolone Chemical Name: Syntex and Eli Lilly Half Life: Dan's educational emphasis is on performance enhancement drugs PEDs , endocrinology, nutritional supplements and strategies for health, fat reduction, anti-ageing, muscle growth, disease control and vaccinations. Dan has had an interest in learning and writing about steroid use for over 15 years.
Overview and History of Masteron Masteron is the trade name for the anabolic steroid Drostanolone.